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Primer on Molecular Genetics
from the U.S. Department of Energy

This primer was prepared by Denise Casey, Human Genome Management Information System, Oak Ridge National Laboratory, for the 1991-92 DOE Human Genome Program Report.

Begin with the Introduction, or use the table of contents below to skip to a specific section. At the bottom of each page is a forward arrow to proceed to the next page and a back arrow to return to the previous page.

• Introduction
  • DNA
  • Genes
  • Chromosomes
• Glossary
• Mapping and Sequencing the Human Genome
  • Mapping Strategies
  • Genetic Linkage Maps
  • Physical Maps
    • Low-Resolution Physical Mapping
      • Chromosomal map
      • cDNA map
    • High-Resolution Physical Mapping
      • Macrorestriction maps: Top-down mapping
      • Contig maps: Bottom-up mapping
  • Sequencing Technologies
    • Current Sequencing Technologies
    • Sequencing Technologies Under Development
    • Partial Sequencing to Facilitate Mapping, Gene Identification
  • End Games: Completing Maps and Sequences; Finding Specific Genes
• Model Organism Research
• Informatics: Data Collection and Interpretation
  • Collecting and Storing Data
  • Interpreting Data
  • Mapping Databases
  • Sequence Databases
    • Nucleic Acids (DNA and RNA)
    • Proteins
• Impact of the Human Genome Project

File last modified May 1997